SEPOY.net
No Result
View All Result
Tuesday, May 20, 2025
  • Home
  • News
  • Business
  • Health
  • Tech
  • Lifestyle
  • Economy
  • Crypto
  • Travel
  • Home
  • News
  • Business
  • Health
  • Tech
  • Lifestyle
  • Economy
  • Crypto
  • Travel
No Result
View All Result
SEPOY.NET
No Result
View All Result
Home Health

Bilateral total knee arthroplasty may increase risk of complications

Nicholas by Nicholas
July 8, 2023
in Health
0
Bilateral total knee arthroplasty may increase risk of complications

Patients undergoing bilateral total knee arthroplasty (TKA) are at an increased risk of several types of complications, as compared with matched patients undergoing unilateral TKA, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

READ ALSO

Headway in Alzheimer’s disease care: New guidance provides recommendations for use of anti-amyloid monoclonal antibodies

Red blood cells drive blood vessel damage in diabetes by exporting toxic vesicles

“Patients who underwent simultaneous bilateral TKA were at higher risk of experiencing postoperative complications such as pulmonary embolism, stroke, blood loss anemia, and requiring a transfusion,” according to the report by Nathanael D. Heckmann, MD, and colleagues of Keck School of Medicine of USC, Los Angeles.

Study in matched groups of patients clarifies risks of bilateral TKA

TKA is a highly effective treatment for patients with advanced osteoarthritis of the knee, decreasing pain and improving function. When both knees are affected, bilateral TKA offers some advantages over sequential unilateral TKA, including less time in the hospital, a single rehabilitation period, and lower overall costs.

However, some studies have found an increased risk of complications, along with a higher mortality rate, in patients undergoing bilateral TKA. These studies have had important limitations, including a lack of patient matching to account for potential differences between those undergoing bilateral versus unilateral TKA. To address these issues, Dr. Heckmann and colleagues compared complications and mortality in a large, nationally representative group of patients undergoing bilateral versus unilateral TKA.

The analysis included more than 21,000 patients undergoing simultaneous bilateral TKA. These were matched for age, sex, race, and comorbidities with a cohort of 126,000 patients undergoing unilateral TKA. After matching, the two groups had an average age of 64 years with similar comorbidities. As all TKAS were performed between 2015 and 2020, the surgical procedures reflected modern orthopaedic practice.

Stroke, transfusion, and other risks higher following bilateral TKA

Patients in the simultaneous bilateral TKA group had increased rates of several types of complications compared with those in the unilateral TKA group, pulmonary embolism (0.27% versus 0.13%), stroke (0.13% versus 0.06%), and respiratory failure (0.46% versus 0.34%).

Patients undergoing bilateral TKA were also at a higher risk of anemia due to blood loss (26.89% versus 14.86%) and were more likely to undergo a blood transfusion (5.23% versus 0.67%). These risks were increased despite the high use of tranexamic acid to reduce blood loss during surgery in both groups.

Patients undergoing bilateral TKA were also more likely to be readmitted to the hospital within 90 days (2.80% versus 2.05%). There was no significant increase in the risk of in-hospital death (0.05% versus 0.04%).

After adjusting for confounders, the risks of pulmonary embolism, stroke, and acute blood loss anemia were approximately doubled in the bilateral TKA group, while the risk of blood transfusion was nearly nine times higher. The risk of readmission within 90 days was 35% higher with bilateral compared with unilateral TKA.

“This study presents the largest matched sample size to date comparing the complications and safety between patients treated with simultaneous bilateral TKA and those treated with unilateral TKA,” Dr. Heckmann and coauthors write. Although there was no significant difference in the rate of in-hospital death, “The risk of mortality following simultaneous bilateral TKA is still a topic of concern.” The researchers emphasize the need for patient counseling and “thorough medical optimization” in patients selected for bilateral TKA.

Tags: AnemiaArthroplastyBloodBlood TransfusionBoneEmbolismHealthcareHospitalKneeKnee ArthroplastyMedicineMortalityOrthopaedicOsteoarthritisPainPulmonary EmbolismResearchStrokeSurgeryTechnology

Related Posts

Headway in Alzheimer’s disease care: New guidance provides recommendations for use of anti-amyloid monoclonal antibodies
Health

Headway in Alzheimer’s disease care: New guidance provides recommendations for use of anti-amyloid monoclonal antibodies

May 20, 2025
Red blood cells drive blood vessel damage in diabetes by exporting toxic vesicles
Health

Red blood cells drive blood vessel damage in diabetes by exporting toxic vesicles

May 19, 2025
Zebrafish study reveals hidden dangers of environmental toxins from tires
Health

Zebrafish study reveals hidden dangers of environmental toxins from tires

May 19, 2025
Study explores impact of overlapping conditions on heart failure outcomes in older adults
Health

Study explores impact of overlapping conditions on heart failure outcomes in older adults

May 19, 2025
Karger Publishers releases free-access eBook "Healthy Aging"
Health

Karger Publishers releases free-access eBook "Healthy Aging"

May 19, 2025
Repeated antibiotics in preterm infants linked to long-term lung problems
Health

Repeated antibiotics in preterm infants linked to long-term lung problems

May 19, 2025
Next Post
At least two dead in Gulf of Mexico oil rig explosion

At least two dead in Gulf of Mexico oil rig explosion

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

About

Sepoy.net is a perfect place for people who want daily updates on news related to business, technology, entertainment, health, cryptocurrency etc.

Contact: hello@sepoy.net

Major Categories

News

Business

Tech

Economy

 

Recent Posts

  • Headway in Alzheimer’s disease care: New guidance provides recommendations for use of anti-amyloid monoclonal antibodies
  • LiveBlog USA under Trump: Supreme Court enables deportations of Venezuelans for the time being
  • Huione Group の閉鎖は暗号資産による詐欺インフラにどのような影響をもたらすか

Pages

  • About Us
  • Contact Us
  • Disclaimer
  • DMCA
  • Home
  • Privacy Policy

© 2023 Sepoy.net

No Result
View All Result
  • Home
  • Business
  • News
  • Health
  • Tech
  • Science
  • Lifestyle
  • Travel

© 2023 Sepoy.net