Sepoy-logo
No Result
View All Result
Wednesday, March 22, 2023
  • Home
  • News
  • Business
  • Health
  • Tech
  • Lifestyle
  • Economy
  • Crypto
  • Travel
  • Home
  • News
  • Business
  • Health
  • Tech
  • Lifestyle
  • Economy
  • Crypto
  • Travel
No Result
View All Result
SEPOY.NET
No Result
View All Result
Home Health

New imaging agent lights the way for surgeons during lung cancer surgery

Nicholas by Nicholas
December 19, 2022
in Health
0
New imaging agent lights the way for surgeons during lung cancer surgery

Surgery, especially surgery to remove cancerous tumors, relies on a range of tools and techniques as well as on the skill of the surgeon. Now, new imaging agent Cytalux will make surgery to remove lung cancer tumors a little more exact.

The inside of the human body famously looks nothing like an anatomy textbook, lacking the bright color coding to differentiate between tissues and organs. Based on foundational intellectual property developed at Purdue University and released by On Target Laboratories, Cytalux helps make tumors more easily and immediately identifiable by illuminating them and making them glow against healthy, noncancerous tissue like beacons against a night sky.

Philip Low (rhymes with “now”), Purdue’s Presidential Scholar for Drug Discovery and the Ralph C. Corley Distinguished Professor of Chemistry in the College of Science, is an inventor of the drug.

Non-small cell lung cancer is one of the deadliest cancers. The only absolute cure for lung cancer is to surgically remove all of the malignant tissue out of the patient. If it has metastasized, it’s generally lethal.”


Philip Low, Purdue University

Lung cancer is the second most commonly diagnosed cancer in the world and accounts for more than a quarter of all cancer deaths in the U.S. every year. When a patient is diagnosed with non-small cell lung cancer, the prognosis is often bleak: Only 7% have a chance of living another five years.

The importance of removing all the malignant tissue, the difficulty in distinguishing cancerous tissue from healthy tissue and the widespread nature of this type of lung cancer make the use of Cytalux in lung cancer surgery a welcome development. Low, a chemist by trade, attacks these issues using his expertise in chemical reactions.

Cytalux exploits the unique chemistry of cancer cells to light up the tumors. Cancer cells divide rapidly, much faster than normal cells. To do this, they need folate, a type of B vitamin -; and lots of it. The genius of Cytalux is that, after being administered intravenously to a patient before surgery, it tags that folate compound with a fluorescent dye. The cancer cells grab for the folate but end up flagged with the fluorescent dye, too. During surgery, these cells then fluoresce under near-infrared light. Low explains further how the drug works in this YouTube video.

The newly authorized use of Cytalux, which was initially developed to target ovarian cancer, has the potential to improve the outcomes of thousands of patients, helping surgeons to visualize otherwise undetected cancer tissue in 24% of lung cancer patients in a clinical trial.

“Cancer cells have an enormous appetite for this vitamin, and we have exploited their greed for folic acid by attaching a fluorescent dye to it,” Low said. “The drug not only allows the surgeon to see the cancer but may also help surgeons avoid removing tissue. Being able to avoid cutting healthy tissue can be as important as removing unhealthy tissues.”

Low and his team continue to develop imaging agents to make cancer tumors easier to detect and remove. He hopes that in the future all solid-tumor cancers will have a targeted fluorescent marker to light the way for surgeons.

“We’re leading the way in this effort,” Low said. “We are pioneers. We were not only the first tumor-targeted fluorescent dye to be approved by the FDA, but we developed a second one close on its heels. We are also working on other tumor-targeted fluorescent dyes to target many other types of cancer.”

Low conducts his research as part of the Purdue Center for Cancer Research. The center is one of only seven basic science laboratory cancer centers recognized by the National Cancer Institute, which is part of the National Institutes of Health. The center brings together more than 110 researchers at Purdue who study cancer at the cellular level.

Low and his team disclosed the innovation in imaging agents to the Purdue Research Foundation Office of Technology Commercialization. OTC applied for patent protection on the intellectual property and licensed it to On Target Laboratories, which is based in West Lafayette, Indiana. Low is the founder and chief science officer of On Target Laboratories.

READ ALSO

Prescription for housing? California wants Medicaid to cover 6 months of rent

Insulin resistance increases retinopathy and nephropathy risk in young type 1 diabetics

Tags: AnatomyCancerCellDrug DiscoveryEducationImagingLung CancerMalignantNon-Small Cell Lung CancerResearchSmall Cell Lung CancerstudentsSurgeryTumor

Related Posts

Prescription for housing? California wants Medicaid to cover 6 months of rent
Health

Prescription for housing? California wants Medicaid to cover 6 months of rent

March 22, 2023
Insulin resistance increases retinopathy and nephropathy risk in young type 1 diabetics
Health

Insulin resistance increases retinopathy and nephropathy risk in young type 1 diabetics

March 22, 2023
Misleading and low-quality Mpox health information in TikTok videos
Health

Misleading and low-quality Mpox health information in TikTok videos

March 22, 2023
Research funding could advance cancer treatment
Health

Research funding could advance cancer treatment

March 21, 2023
Study highlights the role of intestinal T cells in modifying psychological stress responses
Health

Study highlights the role of intestinal T cells in modifying psychological stress responses

March 21, 2023
Research evaluates the effects of physical agents on male fertility
Health

Research evaluates the effects of physical agents on male fertility

March 21, 2023
Next Post
Picking The Best Batteries For Your Electronic Bicycle

Picking The Best Batteries For Your Electronic Bicycle

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

POPULAR NEWS

Roblox Is Unbreakable Trello Is this safe?

Roblox Is Unbreakable Trello Is this safe?

November 4, 2022
Discord Registered Games  Discord Registered Gaming You need to join the Club

Discord Registered Games Discord Registered Gaming You need to join the Club

November 4, 2022
How To Chose the Right Data Analytics Program

How To Chose the Right Data Analytics Program

November 4, 2022
Chandrashekhar Guruji Wiki, Age, Girlfriend, Wife, Family, Biography & More

Chandrashekhar Guruji Wiki, Age, Girlfriend, Wife, Family, Biography & More

November 4, 2022
Heavy explosion on market square in Halle – three injured

Heavy explosion on market square in Halle – three injured

November 4, 2022

EDITOR'S PICK

Creating Best KPI and Making Them Work for Your Company

June 10, 2022

Hiring a Concrete Contractor in Simpsonville, SC

July 16, 2022

Things to Avoid When Choosing an Air Conditioner for an Office

June 24, 2022

Faunt Wordle :- What is the connection between Faunt and Wordle 444?

September 7, 2022

About

Sepoy.net is a perfect place for people who want daily updates on news related to business, technology, entertainment, health, cryptocurrency etc.

Contact: [email protected]

Major Categories

News

Business

Tech

Economy

 

Recent Posts

  • Nvidia partners with Microsoft to accelerate the creation of its Omniverse metaverse
  • 5 Expert Marketing Tips For Attracting Local Traffic To Your Website
  • Prescription for housing? California wants Medicaid to cover 6 months of rent

Pages

  • About Us
  • Contact Us
  • Disclaimer
  • DMCA
  • Home
  • Privacy Policy

© 2023 Sepoy.net

No Result
View All Result
  • Home
  • Business
  • News
  • Health
  • Tech
  • Science
  • Lifestyle
  • Travel

© 2023 Sepoy.net