Ketone metabolism redefines protein quality control in aging brains
Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular processes and aging mechanisms ...
Tag: Autophagy
HMGB1 as a key mediator in liver disease pathogenesis
Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality rates. Acute ...
Drug repurposing offers hope for SYNGAP1 patients
The SynGAP Research Fund 501(c)(3) has awarded a pair of grants to Dr. Clement Chow, a geneticist and Associate Professor ...
The molecular underpinnings by which traumatic brain injury increases Alzheimer's disease risk
Researchers found that traumatic brain injury increases synaptic dysfunction and cognitive impairments linked to developing Alzheimer's disease. Study: Neuronal BAG3 ...
Plant polyphenols: The secret to living longer and healthy aging?
Plant polyphenols show promise in slowing aging, boosting brain health, and preventing age-related diseases through their powerful antioxidant and anti-inflammatory ...
STING protein plays new role in cellular stress clearance and survival
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role ...
A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries
In a recent study published in Nature Metabolism, researchers conducted clinical studies on murine animals and humans to evaluate the ...
Deciphering how amino acids control cell growth and autophagy in yeast
Amino acids are the building blocks of life. We obtain them from the food we eat, and the body uses ...
New insights into how SARS-CoV-2 evades our immune system
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19), possesses a positive-sense ...
New discovery could shift the focus of Parkinson’s disease treatment
Researchers from the University of Queensland have identified that a gene associated with an increased risk of Parkinson's Disease also ...
