Breakthrough in gene-editing with Cas12a for modeling human diseases
Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating human disease. A novel ...
Tag: Cas9
Using advanced CRISPR to boost efficiency of CAR-T cell therapies
CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first ...
CD5 knockout using CRISPR boosts CAR T cell therapy efficacy
The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by ...
Novel method enables RNA detection with Cas12 nucleases
CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers at the Helmholtz ...
ERS Genomics and IRBM sign CRISPR/Cas9 license agreement
ERS Genomics Limited (‘ERS’), the CRISPR licensing Company, and IRBM, a leader in the field of drug discovery, today announced ...
Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness
Retinal degeneration can be inherited or acquired. In the former case, it is an incurable and progressive condition. A recent ...
CRISPR gene editing shows promise for treating individuals with a form of inherited blindness
Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show ...
Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas
In a recent study published in Cell Reports, researchers demonstrated clustered regularly interspersed short palindromic repeats (CRISPR)-mediated elimination of glioblastoma ...
Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9
The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more. In research published ...
New gene therapy shows promise for treating fusion-driven cancers
A new study presents a promising treatment method for so-called fusion-driven cancers, which are currently often difficult to cure. These ...