New CRISPR-based test enhances diagnosis of life-threatening fungal infection
Tulane University researchers have developed a CRISPR-based test that diagnoses Pneumocystis jirovecii pneumonia (PJP) - a life-threatening fungal infection primarily ...
Tag: CRISPR
Breakthrough in gene-editing with Cas12a for modeling human diseases
Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating human disease. A novel ...
Study pinpoints how a network of different proteins controls rest and activation
Cells in the immune system don't always fight; they often rest and wait for threats, like viruses or bacteria. When ...
Aging of lung stem cells drives iron deficiency and reduces capacity for tumor formation
Researchers reveal how aging induces iron insufficiency, reducing stem cell function and tumor growth while enhancing ferroptosis resistance Study: Ageing ...
Scientists map the genetic landscape of drug resistance in cancers
All cancer mutations that cause drug resistance fall into one of four categories. New research has detailed each type, helping ...
Researchers gain new understanding of how immune cells respond to heat during fever
Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and effector function of CD4 T cells while reducing regulatory ...
Using advanced CRISPR to boost efficiency of CAR-T cell therapies
CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first ...
CD5 knockout using CRISPR boosts CAR T cell therapy efficacy
The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by ...
Novel method enables RNA detection with Cas12 nucleases
CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers at the Helmholtz ...
ERS Genomics and IRBM sign CRISPR/Cas9 license agreement
ERS Genomics Limited (‘ERS’), the CRISPR licensing Company, and IRBM, a leader in the field of drug discovery, today announced ...