Using advanced CRISPR to boost efficiency of CAR-T cell therapies
CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first ...
Tag: Gene-Editing
Broken String Biosciences and the Francis Crick Institute collaborate to advance ALS research
Broken String Biosciences (“Broken String”), a genomics company driving development of the next generation of more precise, safe, and effective cell and gene therapies, today ...
CRISPR gene editing shows promise for treating individuals with a form of inherited blindness
Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show ...
Study: Two-thirds of babies with sickle cell disease are born to mothers living in disadvantaged areas
As if starting life with a potentially disabling genetic blood disease wasn't enough, a study shows that almost two-thirds of ...
Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9
The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more. In research published ...
Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection
Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by ...
AI tool promises to accelerate the development of gene therapies on a large scale
An artificial intelligence (AI) program may enable the first simple production of customizable proteins called zinc fingers to treat diseases ...
New CRISPR-based tool can snip out faulty genes and replace them with new ones
Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and ...
MIT researchers develop new technique for genome-wide studies of the liver
The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the ...
What are the current challenges and future directions of mRNA nanomedicine?
In a recent review published in Nature Medicine, researchers presented challenges related to the clinical translation of messenger ribonucleic acid ...
