Drug repurposing offers hope for SYNGAP1 patients
The SynGAP Research Fund 501(c)(3) has awarded a pair of grants to Dr. Clement Chow, a geneticist and Associate Professor ...
Tag: Glycosylation
Unlocking the power of lectins: BOA emerges as a potent weapon against all SARS-CoV-2 variants
In a recent article published in Proceedings of the National Academy of Sciences, researchers evaluate the potency of antiviral lectins against ...
Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes
Within the renin-angiotensin system (RAS), which regulates blood volume, electrolyte balance, and systemic vascular resistance within the body, the angiotensin-converting ...
Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection
Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by ...
Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro
In a recent study posted to the bioRxiv* preprint server, researchers evaluated the efficacy of small molecule drugs against severe ...
Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants
In a recent study published in the journal Advanced Science, researchers developed molecularly imprinted nanoparticles (nanoMIPs) with broad-spectrum activity against ...
MicroRNAs can upregulate proteins in addition to downregulating protein production
microRNAs can play a role in cancer development and are thought to exclusively suppress protein expression in dividing cells, such ...
Study indicates widespread SARS-CoV-2 exposure in wildlife
In a recent study posed to the bioRxiv* preprint server, researchers at Virginia Tech University investigated wildlife exposure to SARS-CoV-2 ...
What is the role of N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 spike maturation?
A recent study published in Science Advances showed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike N-glycosylation patterns, intracellular lectins, as ...
Exploration of glycan shield structure of sarbecoviruses provides new insights into developing pan-coronavirus vaccines
A recent study posted on the bioRxiv* preprint server explored the glycan shield diversity of sarbecoviruses, furthering the knowledge for ...
