Unveiling the role of auto-antibodies in COVID-19 severity
Even though COVID-19 manifests as a mild and short-lived disease in most people, some suffer extremely severe symptoms; in the ...
Tag: Interferons
Study reveals key protein's role in balancing immune response to viral infections
Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response ...
New insights into how SARS-CoV-2 evades our immune system
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19), possesses a positive-sense ...
Intranasal inoculation study sheds light on nasal and systemic immune responses to SARS-CoV-2
In a recent pre-print uploaded to the medRxiv server, researchers inoculated 34 healthy volunteers with a pre-Alpha severe acute respiratory ...
Self-directed autoantibodies against certain chemokines may protect against long-COVID
A recent study published in the journal Nature Immunology discovered autoantibodies against chemokines following severe acute respiratory syndrome coronavirus 2 ...
How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals display a wide range of clinical variations, from asymptomatic infection to lethal ...
SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients
In a recent study posted to the medRxiv* preprint server, a team of researchers characterized the expression of type-1 and ...
The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism
In a recent study posted to the bioRxiv* server, researchers explored the role of the open reading frame 3c (ORF3c), ...
Study identifies mechanism behind 'cytokine storm' in COVID-19 patient lungs
A new study by HSS Research Institute scientists identifies a mechanism by which SARS-CoV-2 induces the inflammatory response in COVID-19 ...
Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution
In a recent study published in PNAS, researchers compared the potency of 17 human interferons (IFNs) against multiple severe acute ...
