Researchers make breakthrough in understanding the role of tau protein in Alzheimer's
A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau ...
Tag: Knockout
How gut microbes and hormones shape your sweet tooth
Researchers discover a gut-microbe-driven pathway involving pantothenate and GLP-1 that could revolutionize sugar consumption management and metabolic health strategies. Study: ...
Setd2 catalytic activity is crucial for embryonic development in mice
A recent study delves into the pivotal role of Setd2, a histone methyltransferase enzyme, in embryonic development within mice. Setd2 ...
ASTN2 gene knockout in mice reveals key autism-related behaviors
More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the ...
CD5 knockout using CRISPR boosts CAR T cell therapy efficacy
The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by ...
Neuropathic pain study uncovers pathophysiological mechanism and promising therapeutic target
Neuropathic pain -; abnormal hypersensitivity to stimuli -; is associated with impaired quality of life and is often poorly managed. ...
New study aims to elucidate the role of p21 in chronic lung inflammation
A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" ...
An emerging target for chronic kidney disease treatment – DNA-PKcs
Around 10% of the global population is affected by chronic kidney disease (CKD). The risk of CKD progressing into end-stage ...
Study reveals the mechanism through which Sirtuin 7 protein suppresses thermogenesis in mice
Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis. This process is ...
Researchers uncover the host protease CAPN2 as a novel host factor that aids the infection of SARS-CoV-2
In a recent study posted to the bioRxiv* preprint server, researchers investigated the potential of the calpain-2 (CAPN2) molecule as ...
