Mayo Clinic researchers advocate for comprehensive TPMT genotyping across ancestries
Mayo Clinic researchers found that a gene variant, the TPMT∗8 allele, is associated with reduced metabolism of the thiopurine class ...
Tag: Leukemia
Mapping blood system changes offers new hope for leukemia treatments
Researchers at University of California San Diego School of Medicine and their colleagues have developed the first comprehensive map of ...
UC's Eric Vick receives major grants to advance research into combination therapy for leukemia
The University of Cincinnati Cancer Center's Eric Vick, MD, PhD, has been awarded a nearly $215,000 Career Development Award from ...
%2c_analyze_by_microscope-Jarun_Ontakrai_8864dd9cfb3b4dff9a913aede7a7c915-620x480.jpg "Leukemia cells depend on P-bodies for growth and survival")
Leukemia cells depend on P-bodies for growth and survival
An international team of scientists has uncovered a mechanism by which acute myeloid leukemia (AML) cells sustain their growth. Researchers ...
Review of fasting-mimicking diets in cancer treatment
In a recent review published in Cell Metabolism, researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in ...
Using advanced CRISPR to boost efficiency of CAR-T cell therapies
CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first ...
CD5 knockout using CRISPR boosts CAR T cell therapy efficacy
The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by ...
Novel therapy can improve the prognosis of relapsed/refractory acute myeloid leukemia
Relapsed/refractory acute myeloid leukemia (AML), a so-called blood cancer, has an extremely poor prognosis because of resistance to anti-cancer drugs ...
CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma
CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear ...
Comprehensive cost and utilization of commercial CAR-T therapy in pediatric B-ALL patients
A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "The price of hope: CAR-T ...
