Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors
B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common ...
Tag: Preclinical
Groundbreaking stem cell therapy trial for Alzheimer's disease underway at UTHealth Houston
A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer's disease is underway at UTHealth Houston. In ...
Combination of RAS inhibition and immunotherapy provides breakthrough for pancreatic cancer
Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic ...
Insilico Medicine's AI-driven drug Rentosertib receives official generic name
Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, recently announced that its breakthrough drug candidate for idiopathic ...
Microphysiological systems in drug discovery
What are the challenges of drug development? Drug development is a very challenging and often arduous process with many associated ...
Neurofilament light as a translational biomarker from preclinical drug discovery to clinical application
In this interview, industry expert Phillip Mitchell discusses the role of NfL biomarkers in CNS drug discovery, neurodegenerative disease research, ...
Researchers discover strategy to slow brain metastases growth in melanoma
Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers at ...
Researchers discover key to boosting thymus regeneration after damage
A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer ...
Estrogen's role in female binge drinking revealed by preclinical study
The hormone estrogen regulates binge drinking in females, causing them to "pregame" – consume large quantities of alcohol in the ...
Cleveland Clinic study reveals kidney microbiome's role in renal health
Cleveland Clinic researchers have found definitive proof of a kidney microbiome that influences renal health and kidney stone formation, demonstrating ...