Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors
B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common ...
Tag: Tumor
New drug combination shows promise in treating melanoma brain metastasis
A federally funded research team led by Sheri Holmen, PhD, investigator at Huntsman Cancer Institute and professor in the Department of Surgery at ...
Breast cancer survivors face accelerated aging tied to tumors and treatment
Many breast cancer (BC) survivors experience accelerated aging, potentially due to the cancer itself or the effects of various treatments. ...
Combination of RAS inhibition and immunotherapy provides breakthrough for pancreatic cancer
Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic ...
Pitt study uncovers a novel trigger of deadly form of ovarian cancer
Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset ...
Novel regulators in digestive tract disease progression and treatment
This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive tract ...
Ovarian cancer mutations across populations show similarities and unique differences
An extensive tumor genomic analysis of individuals with ovarian cancer, led by researchers from Huntsman Cancer Institute at the University of Utah (the U) ...
Circular RNA plays key role in cancer biology and therapy
A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a ...
Ubiquitination plays a key role in cancer stem cell function and treatment resistance
This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on ...
EZH2 inhibition offers hope for fighting treatment-resistant cancers
The critical role of EZH2, an essential epigenetic regulator, in cancer progression and treatment is underscored in this new review ...