Machine learning identifies cancer-driving mutations at CTCF binding sites
In a recent study published in the journal Nucleic Acids Research, researchers investigate whether machine learning can identify pan-cancer mutational ...
Tag: binding affinity
Omicron variant BA.2.86 spreads faster, but current antivirals hold the line
In a recent research paper uploaded to the bioRxiv preprint* server, researchers evaluated the virological characteristics of a novel severe ...
New study reveals BA.2.86 subvariant's surprising dance with antibodies
In a recent study posted to the bioRxiv* preprint server, a team of researchers from the United States examined the ...
Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike
*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide ...
Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants
*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide ...
Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies
In a recent study published in Immunity, researchers isolated SARS-CoV-2 spike (S) protein-targeted mAbs (monoclonal antibodies) from convalescent healthcare workers ...
Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants
In a recent study posted to the bioRxiv* preprint server, a team of researchers from the United States computationally modified ...
Deep mutational scanning for SARS-CoV-2 Omicron BA.1 and BA.2 subvariants
In a recent study posted to the bioRxiv* preprint server, researchers performed deep mutational scanning (DMS) for the severe acute ...
SARS-CoV-2 Omicron BA.4.6 resistant to many therapeutic monoclonal antibodies in clinical use
In a recent study posted to the bioRxiv* preprint server, researchers in Taiwan and the United States explore the resistance ...
The use of AlphaFold2-enabled molecular docking simulations to predict protein-ligand interactions for antibiotic drug discovery
In a recent study published in Molecular Systems Biology, researchers demonstrated that advances in modeling protein-ligand interactions using machine learning-based ...
