Tim-3 identified as promising therapeutic target for Alzheimer's disease
Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer's disease (AD), but its ...
Tag: Immunotherapy
Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors
B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common ...
New drug combination shows promise in treating melanoma brain metastasis
A federally funded research team led by Sheri Holmen, PhD, investigator at Huntsman Cancer Institute and professor in the Department of Surgery at ...
Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder
A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, ...
Combination of RAS inhibition and immunotherapy provides breakthrough for pancreatic cancer
Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic ...
Unraveling the genetic differences between LUAD and LUSC in lung cancer
Lung cancer remains one of the leading causes of cancer-related mortality, with lung adenocarcinoma (LUAD) and lung squamous cell carcinoma ...
New dual-target therapy offers hope for better breast cancer treatment
Researchers, led by the University of Melbourne's Professor Laura Mackay, a Laboratory Head and Immunology Theme Leader at the Peter ...
New mechanism of immune evasion discovered in cancer cells
The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells ...
Researchers discover strategy to slow brain metastases growth in melanoma
Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers at ...
Immune system discovery could revolutionize treatment for chronic disease and cancer
A discovery about the mechanisms that enable the immune system to sustain long-term protection could revolutionize treatment for chronic disease ...