Long-term survival achieved in stage III melanoma with pre-surgery immunotherapy
Four years after pre-surgery treatment with a novel combination of immune checkpoint inhibitors, nivolumab and relatlimab, 87% of patients with ...
Tag: Immunotherapy
How hydrogels are shaping the future of targeted cancer drug delivery
Researchers unveil the global hotspots and next frontiers for hydrogel-based cancer therapies, offering new hope for more precise and less ...
Exercise improves cancer outcomes by shaping the gut microbiome
A new study from the University of Pittsburgh shows for the first time how exercise improves cancer outcomes and enhances ...
Reversing immune fatigue offers new hope for cancer treatment
CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile ...
PPP2R1A mutations linked to improved survival in ovarian clear cell carcinoma
Patients with ovarian clear cell carcinoma (OCCC) whose tumors have specific mutations in the PPP2R1A gene were found to have ...
Rare pancreatic cancer patients show remarkable outcomes with immunotherapy
A new research paper was published in Volume 16 of Oncotarget on June 10, 2025, titled "Exceptional responders to immunotherapy in pancreatic cancer: ...
Advancing precision oncology in intrahepatic cholangiocarcinoma
ICCA accounts for 10–15% of primary liver cancers and is notorious for late-stage diagnosis and resistance to chemotherapy and radiotherapy. ...
_on_a_T-cell_is_binding_to_a_molecule_on_a_cancer_-_Alpha_Tauri_3D_Graphics_M1_dc8762afeaee4937ad644739f274c7a5-620x480.jpg "Boosting CAR T cell survival to improve solid tumor therapy")
Boosting CAR T cell survival to improve solid tumor therapy
Marcela Maus, MD, PhD, director of the Cellular Immunotherapy Program and the Paula J. O'Keeffe Endowed Chair of the Mass General ...
Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors
B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common ...
New drug combination shows promise in treating melanoma brain metastasis
A federally funded research team led by Sheri Holmen, PhD, investigator at Huntsman Cancer Institute and professor in the Department of Surgery at ...